Abnormal pupillary light reflex with chromatic pupillometry in G aucher disease

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Abnormal pupillary light reflex with chromatic pupillometry in Gaucher disease

The hallmark of neuronopathic Gaucher disease (GD) is oculomotor abnormalities, but ophthalmological assessment is difficult in uncooperative patients. Chromatic pupillometry is a quantitative method to assess the pupillary light reflex (PLR) with minimal patient cooperation. Thus, we investigated whether chromatic pupillometry could be useful for neurological evaluations in GD. In our neuronop...

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Effect of Topical Anti-Glaucoma Medications on Late Pupillary Light Reflex, as Evaluated by Pupillometry

PURPOSE The late post-illumination pupillary response (PIPR 10-30s ) to blue light is reduced in glaucoma, suggesting that pupillometry can be used in clinical glaucoma evaluation. Since animal studies have indicated that common anti-glaucomatous agents affect the iris muscle, we investigated the short-term effect of the anti-glaucoma drugs on the pupillary light reflex and in particular on the...

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The pupillary light reflex in normal subjects.

In 19 normal subjects the pupillary reflex to light was studied over a range of stimulus intensities by infrared electronic pupillography and analysed by a computer technique. Increasing stimulus intensity was associated with an increase in direct light reflex amplitude and maximum rate of constriction and redilatation. Latency from stimulus to onset of response-decreased with increasing stimul...

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Atypical Pupillary Light Reflex in Individuals With Autism

We investigated pupillary light reflex (PLR) in 152 children with ASD, 116 typically developing (TD) children, and 36 children with non-ASD neurodevelopmental disorders (NDDs). Heart rate variability (HRV) was measured simultaneously to study potential impairments in the autonomic nervous system (ANS) associated with ASD. The results showed that the ASD group had significantly longer PLR latenc...

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Pupillary light reflex to light inside the natural blind spot

When a light stimulus covers the human natural blind spot (BS), perceptual filling-in corrects for the missing information inside the BS. Here, we examined whether a filled-in surface of light perceived inside the BS affects the size of the short-latency pupillary light reflex (PLR), a pupil response mediated by a subcortical pathway for unconscious vision. The PLR was not induced by a red surf...

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ژورنال

عنوان ژورنال: Annals of Clinical and Translational Neurology

سال: 2014

ISSN: 2328-9503,2328-9503

DOI: 10.1002/acn3.33